“Severe Adverse Effects”: Doctors Warn Pfizer’s Paxlovid Can Interact With Common Medications
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- “Severe Adverse Effects”: Doctors Warn Pfizer’s Paxlovid Can Interact With Common Medications
by Tyler Durden, https://www.zerohedge.com/
Pfizer’s Covid-19 treatment that’s definitely not a profitable Ivermectin knockoff (despite both functioning as protease inhibitors) turns out to pose an increased risk of severe illness in Covid-19 patients who have a history of cardiovascular disease.
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Paxlovid – Pfizer’s Covid medication notably taken by Joe Biden, Jill Biden and Dr. Anthony Fauci – before all three had “rare” (and then not-so rare) cases of “rebound Covid” – can have dangerous interactions with some of the most common medications for cardiovascular disease, including various statins and heart failure therapies, according to a Wednesday paper published in the Journal of the American College of Cardiology.
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In it, researchers found that the combination of nirmatrelvir and ritonavir, two antivirals which comprise Pfizer’s Paxlovid, can interact with a number of commonly prescribed cardiovascular medications. According to the paper, Ritonavir, which was approved to treat HIV in 1996, impacts the CYP450 pathway that’s involved in metabolizing a number of medications—as well as the P-glycoprotein drug efflux pump, the Epoch Times reports.
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“Co-administration of [Paxlovid] with medications commonly used to manage cardiovascular conditions can potentially cause significant drug-drug interactions and may lead to severe adverse effects,” reads an abstract. “It is crucial to be aware of such interactions and take appropriate measures to avoid them.”
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