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British Medical Journal Study: Statins Harm More People than They Help

December 15, 2015 by mosesman
http://papers.ssrn.com/sol3/papers.cfm?abstract_id=2282014
Click on image for article.
  • British Medical Journal Study: Statins Harm More People than They Help
    by Tony Isaacs, http://www.tbyil.com/ 
    We are told by the medical profession that drugs are prescribed based on a professional estimation of risk versus benefit. Now, a new study published last month in the British Medical Journal has demonstrated that when it comes to statin drugs, what benefits that might be realized by a tiny number of people are outweighed by a larger risk of harm.
    –
    The study was conducted by the University of Nottingham’s Julia Hippisley-Cox, professor of clinical epidemiology and general practice, and Carol Coupland, associate professor in medical statistics. In the study, the researchers measured he unintended effects of statins. They studied data on 2,004,692 patients aged 30-84 years including 225,922 patients who were new statin users which was collected from 368 general practices in England and Wales.
    –
    Despite all the years of the pharmaceutical industry claiming that statin drugs are virtual “miracle” medicines which not only prevent millions of heart attacks and strokes but also have numerous other benefits, the new study found just the opposite. According to the study results, only a few people benefitted from decreased risk of serious coronary events, and, other than a small statistical improvement for risk of esophageal cancer, no other benefits were found whatsoever. On the other hand, the study found significant increased risks for moderate or serious liver dysfunction, acute renal failure, moderate to serious myopathy and cataracts and evidence of a dose response for acute renal failure and liver dysfunction with higher doses being associated with greater risk.
    –
    Overall, for every 10,000 high risk women treated with statins, there would be approximately 271 fewer cases of cardiovascular disease, 8 fewer cases of oesophageal cancer; 74 extra patients who experience liver dysfunction; 23 extra patients with acute renal failure, 307 extra patients with cataracts, and 39 extra patients with myopathy.
    –
    The study concluded: “Claims of unintended benefits of statins, except for oesophageal cancer, remain unsubstantiated, although potential adverse effects at population level were confirmed and quantified. Further studies are needed to develop utilities to individualise the risks so that patients at highest risk of adverse events can be monitored closely.”
    –
    The increased risks for most of the conditions identified returned to near normal within one to three years after discontinuing statin use, with the exception that the risk of extreme muscle weakness (myopathy) remained significantly higher even after three years of discontinuing statin use.
    –
    By the pharmaceutical companies own admission, most drugs don’t work on most people. When it comes to statin drugs, they only “work” on about 2.7% of the time while causing serious damage in about 4.4% of those who take them. Put another way, if you take statin drugs, you have less than 3 in 100 odds of benefitting and over 4 in 100 odds of being harmed. Over 92 out of every 100 people would be neither helped nor seriously harmed, but would nevertheless be needlessly enriching the drug companies while polluting our waterways and water supplies every time they flush the toilet.
    –
    read more.
http://www.bmj.com/content/340/bmj.c2197.full
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http://www.independent.co.uk/news/science/glaxo-chief-our-drugs-do-not-work-on-most-patients-575942.html
Click on image for article.
http://www.umass.edu/newsoffice/article/several-fda-approved-anti-cancer-drugs
Click on image for article.

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